Laminil treatment for laminitic horses looks promising

Laminitis, or inflammation of the hoof, has existed possibly since the 17th century B.C., but it’s taken almost 4,000 years for someone to come up with a way to stop an acute bout of the disease.

That someone is Colorado researcher Charlie Owen, who has developed an injectable drug called Laminil, which could be a game changer in the treatment of laminitis.

Laminil is a mast cell stabilizer designed to inhibit inflammatory mediators and other chemicals from being released from the mast cell in excess, halting inflammation in the hoof, which can destroy the connective tissue that holds the coffin bone in place.

The drug doesn’t solve the problem of what triggers laminitis. Horse owners will still have to deal with that. This drug may save the hoof and buy owners time to play detective.

Laminil has shown promise in stopping an acute or active chronic case of laminitis. All of the horses treated in a clinical trial in spring 2013 showed improvement, and at least one returned to work within a few months.

The active ingredient in the drug is already FDA approved for humans.

Laminil is injected above the fetlock, and treatment seems like a pretty easy process.

Owen has been working on this drug since 1992. I have been following his progress for a long time, because his premise of using a mast cell stabilizer to interfere with the immune system always seemed sound to me. Clearly, my horses were having some sort of an immune reaction when they developed laminitis. As I’ve described in the past, they would break out with weeping sores, including during the winter, and no one is going to convince me those sores were from insect bites.

In the spirit of full disclosure, I have been lending my web skills to Owen since 2013. I have been posting content to his website and and helped him put together a video on laminitis and Laminil. I am not an employee. I believe in his product and will move mountains to try to help him get it through the FDA process.

Watch the video if you want to see the possibilities with Laminil.




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